CVE-2026-31969

HIGH

HTSlib CRAM decoder has a heap buffer overflow

Title source: cna
STIX 2.1

Description

HTSlib is a library for reading and writing bioinformatics file formats. CRAM is a compressed format which stores DNA sequence alignment data using a variety of encodings and compression methods. When reading data encoded using the `BYTE_ARRAY_STOP` method, an out-by-one error in the `cram_byte_array_stop_decode_char()` function check for a full output buffer could result in a single attacker-controlled byte being written beyond the end of a heap allocation. Exploiting this bug causes a heap buffer overflow. If a user opens a file crafted to exploit this issue, it could lead to the program crashing, or overwriting of data and heap structures in ways not expected by the program. It may be possible to use this to obtain arbitrary code execution. Versions 1.23.1, 1.22.2 and 1.21.1 include fixes for this issue. There is no workaround for this issue.

Scores

CVSS v3 8.1
EPSS 0.0005
EPSS Percentile 16.3%
Attack Vector NETWORK
CVSS:3.1/AV:N/AC:L/PR:N/UI:R/S:U/C:N/I:H/A:H

CISA SSVC

Vulnrichment
Exploitation none
Automatable no
Technical Impact partial

Details

CWE
CWE-122 CWE-787
Status published
Products (5)
htslib/htslib 1.23
htslib/htslib < 1.21.1
samtools/htslib < 1.21.1
samtools/htslib = 1.23
samtools/htslib >= 1.22, < 1.22.2
Published Mar 18, 2026
Tracked Since Mar 19, 2026