CVE-2026-31971

HIGH

HTSlib CRAM decoder vulnerable to buffer overflow

Title source: cna
STIX 2.1

Description

HTSlib is a library for reading and writing bioinformatics file formats. CRAM is a compressed format which stores DNA sequence alignment data using a variety of encodings and compression methods. When reading data encoded using the `BYTE_ARRAY_LEN` method, the `cram_byte_array_len_decode()` failed to validate that the amount of data being unpacked matched the size of the output buffer where it was to be stored. Depending on the data series being read, this could result either in a heap or a stack overflow with attacker-controlled bytes. Depending on the data stream this could result either in a heap buffer overflow or a stack overflow. If a user opens a file crafted to exploit this issue it could lead to the program crashing, overwriting of data structures on the heap or stack in ways not expected by the program, or changing the control flow of the program. It may be possible to use this to obtain arbitrary code execution. Versions 1.23.1, 1.22.2 and 1.21.1 include fixes for this issue. There is no workaround for this issue.

Scores

CVSS v3 8.1
EPSS 0.0014
EPSS Percentile 33.9%
Attack Vector NETWORK
CVSS:3.1/AV:N/AC:L/PR:N/UI:R/S:U/C:N/I:H/A:H

CISA SSVC

Vulnrichment
Exploitation none
Automatable no
Technical Impact partial

Details

CWE
CWE-121 CWE-122 CWE-1284 CWE-787
Status published
Products (5)
htslib/htslib 1.23
htslib/htslib < 1.21.1
samtools/htslib < 1.21.1
samtools/htslib = 1.23
samtools/htslib >= 1.22, < 1.22.2
Published Mar 18, 2026
Tracked Since Mar 19, 2026